HENRY PLATT CUSHING

Michael Platt

operates in a number of them and earns there only around £30 million. Despite the concerns, many still believe Witty’s pledge marks a major step forward for neglected diseases and developing countries. “He is breaking the mould in validating the concept of patent pools,” said Rohit Malpani at Oxfam’s access to medicines campaign. “It is a big step forward. It is welcome that he is inviting othe...

Len Platt , Tobias Becker and David Linton

Several months before the outbreak of the First World War, a new piece of popular musical theatre opened at the Gaiety Theatre in London’s West End. After the Girl told the story of Doris Pitt, the daughter of a Cincinnati millionaire sent to Brussels to complete her education. When her father arrives on a visit in Paris, he finds her ‘corrupted’ and determines to send her back home. Doris, how...

Harvey Cushing

Preventing Cushing: Iatrogenic Cushing Syndrome due to Ritonavir-Fluticasone Interaction

Ritonavir is commonly used in low doses to boost plasma levels of protease inhibitors in patients with human immunodeficiency virus (HIV) infections. It is also a potent inhibitor of cytochrome P450. We present a 50-year-old African American male with past medical history of HIV on highly active antiretroviral therapy (HAART), which also included ritonavir and long standing asthma that has been...

Cushing ' S Syndrome

In 1932 Harvey Cushing described a number of patients presenting a similar clinical picture which he had collected from the literature, and he added two more from his own records. The presence of minute adenomata of basophil cells in the anterior lobe of the pituitary gland was demonstrated at autopsy on some of them and Cushing regarded these as the causative lesions and called the syndrome 'p...